GRObio has a distinguished scientific and business team – world-renowned pioneers with decades-long careers dedicated to genome engineering, computational biology, and therapeutic development
- Our science emerged from some of the most distinguished labs in the world. Our founders developed our platform technologies in the labs of George Church at Harvard Medical School and Andrew Ellington at University of Texas, Austin, pioneers of synthetic biology.
- We are supported by top-tier investors that have a proven track record of success in developing biotechnology platforms, commercializing novel therapies, and driving exponential growth in value. Our business team has closed over $2B in transactions.
- We have highly engaged, world-class advisors for specific disease indications that have led commercialization of blockbuster drugs, and have held top-level positions in academia and industry. Our Commercialization Advisory Board has decades of experience in drug discovery, clinical development and partnership transactions.
- Our core values are courage, learning, openness, and humility, and we believe we’re building something revolutionary with near limitless possibilities to improve health outcomes for patients. Check out our career openings.
Our Approach
We aim to identify and solve holy grail problems in medicine. We search for unmet clinical needs that our platform can uniquely address. From autoimmune conditions to metabolic diseases, we’re only scratching the surface of possibilities to improve the lives of patients.
We’re striving to fulfill the promise of protein-based therapies by reprogramming biology. Our GRO platform creates novel proteins with an expanded alphabet of non-standard amino acids (NSAAs), providing therapeutic modalities that were previously impossible. Our production process is scalable, stable, and sustainable.
GRObio’s mission is to leverage the unprecedented capabilities of NSAAs in our GRO platform to overcome longstanding limitations in protein therapeutics and bring better health outcomes to patients. Our Biofoundry pairs computational protein design with sophisticated robotics, bringing sea-change acceleration to the development of NSAA therapeutics.
We’re applying our groundbreaking science to advance partnered and collaborative programs, as well as our own pipeline of unique NSAA therapeutics with the promise of unprecedented potency, stability, and immunotolerance.
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Our Team
The GRObio team has distinguished scientific credentials and a track record of commercial success. We are world-renowned pioneers with decades-long careers of innovation in protein engineering and pharmaceutical development.
Our executive leadership, directors and advisors bring together some of the best minds in synthetic biology, drug development and corporate strategy. We’ve built a team-based culture that values comradery and ownership of ideas to propel our vision to redefine protein-based therapies.
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Dr. Lodie brings more than 20 years of experience in the biopharmaceutical industry focused on the discovery and development of cell therapies and novel biologics in the areas of autoimmunity, transplant biology, and immuno-oncology. She is an expert in immunology, clinical translation, development, and commercialization. Prior to GRObio, she was Chief Scientific Officer of Quell Therapeutics and Gamida Cell, Ltd. Previously she held senior leadership roles at Blue Rock Therapeutics, Syros Pharma, and Sanofi/Genzyme where she led immunology efforts from discovery through early clinical development to FDA approvals. Dr. Lodie completed postdoctoral work in hematology/oncology at Harvard Medical School. She holds a PhD in immunology and pathology from Boston University School of Medicine and a BS in biology from Fairfield University.
Mr. Stewart, a veteran industry executive, has worked extensively in business and corporate development in the biotechnology and pharmaceutical space for more than 20 years. He has played an integral strategic role in scaling platform biotechnology companies from early stages through FDA-approval and product launch. Mr. Stewart served most recently as Chief Business Officer of Ribon Therapeutics. Prior to his role at Ribon he served as President and CEO of Commense, Inc., Chief Business Officer of Crescendo Biologics, and spent many years with Merrimack Pharmaceuticals in various roles, including SVP of Business Development and Head of Commercial. Mr. Stewart received his MBA from Cornell University.
Precillia is a deeply experienced practitioner of human resources, organizational effectiveness, organizational design and change management. She has worked in the start-up, biotechnology and pharmaceutical spaces. Precillia has worked with clients of all sizes in the therapeutics space, including Gemini Therapeutics, where she served as Chief People Officer. Precillia also worked for Liberty Mutual Insurance as the Vice President of Organizational Effectiveness (OE), and Strategy & Planning for the HR function (Talent & Enterprise Services) – a 1,400 employee organization serving over 50,000 employees globally. Precillia holds a Foundations of Coaching Certificate in Leadership Coaching from Case Western Reserve University, an MBA from the F.W. Olin Graduate School of Business at Babson University, and a BA in International Relations and French from American University.
Dr. Bitterman is a partner at Atlas Venture. He focuses on creating and investing in companies that translate groundbreaking science into innovative medicines. Dr. Bitterman is board chair at Chroma Medicine and was the founding CEO of Editas Medicine, Morphic Therapeutic (acquired by Lilly), and Visterra (acquired by Otsuka). He previously served as a director of Akero Therapeutics, Mariana Oncology (acquired by Novartis), Vedere Bio (acquired by Novartis), and Taris Biomedical (acquired by Johnson & Johnson) among other ventures. He received a BA in biology, with highest honors, from Rutgers University before completing his PhD in genetics at Harvard Medical School.
Dr. Becker is a Managing Director at Access Biotechnology where he invests in private and public companies across therapeutic areas, modalities, and development stages. Prior to Access, Dr. Becker was a Principal at New Leaf Venture Partners and a Principal in the Health Care practice at the Boston Consulting Group. Dr. Becker trained clinically in internal medicine and nephrology at Brigham and Women’s Hospital and Massachusetts General Hospital, and was a Research Fellow at Harvard Medical School. He obtained both his MD and PhD (Cellular and Molecular Biology) degrees from the University of Michigan and received his BS in Physiology from the University of Illinois at Urbana-Champaign.
Ms. Rakhshita Dhar is Senior Director of Venture Investments Health at Leaps by Bayer. Ms. Dhar received her Undergraduate degree in Biochemistry from Mumbai University and her Master’s in Molecular Biology from Georgetown University. Ms. Dhar’s past leadership experience include Director of Business Development at Roche Pharmaceuticals where she led collaborations with Dyno Therapeutics and Rheos Biosciences. She also spent several years at MassBio developing an accelerator program for life-science start-ups.
Mr. Fang is a Managing Director at Redmile Group, LLC, a global healthcare investment firm, where he focuses on investing in private biopharma companies. Before joining Redmile, Mr. Fang was an investor at Safeguard Scientifics and a consultant at McKinsey & Company and ZS Associates and served as an operator at Gilead Sciences. Mr. Fang holds an M.B.A. in Healthcare Management and Finance from The Wharton School and a B.A. in Computer Science from the University of California, Berkeley.
Dr. Beutel is an expert in novel therapeutics and platform research, business development, and company creation. He is focused on strategy, vision, team building and value creation at the interface of science and business, particularly for seed through Series A stage biotech. Dr. Beutel received his PhD in Molecular Biology from University of Wisconsin- Madison. In addition to leadership roles at Abbott and Merck, he has had several different C-level roles in multiple biotech companies including founding COO and Chief Business & Strategy Officer at Dewpoint Therapeutics. Dr. Beutel is currently a Founder CEO at Passkey Therapeutics.
Dr. Church is a synthetic biologist with foundational contributions to genome sequencing, DNA synthesis, multiplex accurate genome editing (MAGE) and protein engineering. Dr. Church is Professor of Genetics at Harvard Medical School, Director of Wyss Inst. SynBio platform, and recipient of awards like Bower, Time100, NAS, NAE. Dr. Church led the development of genomically recoded organisms (GROs) at the core of the GRO Biosciences platform, and leads the company’s Scientific Advisory Board.
Dr. Ellington is the Fraser Professor of Biochemistry at the University of Texas at Austin and is a respected expert in using evolutionary techniques to engineer biopolymers and cells. Dr. Ellington led the development of key protein translational machinery to incorporate non-standard amino acids into proteins using GROs. Dr. Ellington is a GRObio co-founder and serves on the company’s Scientific Advisory Board.
Dr. Paulk is an Assistant Professor of AAV Gene Therapy at the University of California San Francisco, Department of Biochemistry & Biophysics. Her research focuses on pioneering next-generation AAV gene delivery and gene editing platforms. She has developed therapies for gene repair and gene transfer for numerous rare diseases and cancer and has applied high-throughput comparative proteomic and epigenomic approaches to address challenges in fundamental AAV biology. Dr. Paulk earned her B.S. in Medical Microbiology from Central Washington University, her PhD in Viral Gene Therapy from Oregon Health and Science University and completed her Postdoctoral Fellowship in Human Gene Therapy at Stanford University.
Dr. Kaarsholm has 21 years of experience at Novo Nordisk leading development and commercialization of metabolic therapeutics. He has delivered several key metabolic disease therapeutics serving in senior leadership roles in protein engineering. Dr. Kaarsholm provides scientific and commercialization expertise for GRObio’s DuraLogic™ technology.
Arthur Hiller is a Boston-based biopharma executive. Over the last decade, he has been CEO of two early stage companies in the areas of drug discovery and cardiovascular medical devices. He currently provides consulting and business advisory support, and serves in part-time senior executive operating and mentoring roles for a wide range of start-up and early stage companies in the Boston area. His career spans more than 35 years of experience across a wide range of functional areas and sectors of the life sciences and healthcare technology industry, where he has held executive positions in general management, marketing, sales, sales management, and business development at Millennium Pharmaceuticals, Inc., Merck and Co, and two other large, multinational pharmaceutical companies.
Dr. Peattie is veteran life science entrepreneur who currently serves as Managing Partner at SV Bio Ventures. Dr. Peattie has served in senior leadership roles at Valo Health, GlaxoSmithKline, and she served as Director of Business Development in the Office of Technology Development at Harvard University. Previously, Dr. Peattie maintained her own biotechnology consulting firm, Pleiades Advisors, and she also held executive scientific, strategy and planning positions at Cubist Pharmaceuticals, Inc. and at Valeo Medical, Inc., of which she was a co-founder. Dr. Peattie holds an MBA from Harvard Business School and a PhD in Biochemistry & Molecular Biology from Harvard University. She was also a post-doctoral fellow at Stanford University and received her BA in Chemistry from Hollins University.
Dr. Roberts currently serves as CEO of Civetta Therapeutics. He is an accomplished R&D executive with expertise in building companies focused on the discovery and clinical development of innovative new therapeutics. Dr. Roberts has a track record of advancing highly novel targets, biology and pharmacological approaches through to development candidates, into first in human clinical studies and successful clinical proof of concept. Dr. Roberts has experience in startups, small biotech and Big Pharma and he has a proven track record in corporate and business development in/out licensing, mergers and acquisitions, and public financings. Dr. Roberts holds a PhD in Organic Chemistry from University of California, Riverside, and completed his post-doctoral work at University of Bern in Organic Chemistry and Chemical Biology.
