By altering the genetic code in bacteria, researchers have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs’ effectiveness and convenience.
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By altering the genetic code in bacteria, researchers have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs’ effectiveness and convenience.
Thyer R, Shroff R, Klein DR, d'Oelsnitz S, Cotham VC, Byrom M, Brodbelt J, Ellington A (2018) Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains. Nature Biotechnology, EPub ahead of print.
https://www.nature.com/articles/nbt.4154